Atmospheric Pressure Mass Spectrometry


Atmospheric Solids Analysis Probe (ASAP®) mass spectrometry allows direct analysis of samples using an atmospheric pressure ionisation (API) source found on Liquid Chromatography Mass Spectrometry (LCMS) instruments. The ASAP probe permits fast analysis of solid, liquid, tissue, or material (e.g. polymer) samples. ASAP is a low cost alternative ionisation method that is especially useful on commercial high end API mass spectrometers which have the capability of accurate mass and mass-selected fragmentation, such as a Bruker Qh-FTMS, Jeol AccuTOF, ThermoFisher Scientific Orbitrap, or Waters Synapt HDMS.


ASAP® is the trade name from M&M Consulting LLC


  • Does not interfere with normal source operations on most instruments
  • Compatible with ESI/APCI operations (No source change required)
  • Enclosed ion source for safety (vapours are contained inside the source)
  • No sample prep required, solids as well as liquids can be analysed
  • Low picogram sensitivity
  • Ideal for high resolution instruments
  • Good substitute for EI/CI solids probe analysis

Note: requires APCI source

ASAP fitted to APCI source

ASAP probe fitted to Thermo Ionmax APCI source